Step-by-step instructions
- Preheat your oven to 375°F (190°C). Lightly grease a 9×13-inch baking dish to prevent sticking.
- In a large mixing bowl, combine the cream of chicken soup, sour cream, garlic powder, onion powder, black pepper, salt, and paprika until the mixture is smooth.
- Gently stir in the chopped chicken, ensuring it’s well-coated with the creamy mixture.
- Carefully fold in the biscuit pieces, distributing them evenly throughout the chicken mixture.
- Add in the shredded cheese and gently mix everything together, without breaking apart the biscuit pieces too much.
- Transfer the entire mixture into the prepared baking dish and spread it out evenly.
- Bake uncovered for 40–45 minutes, or until the casserole is bubbly and the top is golden brown.
- Allow it to rest for 5–10 minutes before serving so the casserole sets beautifully.
How to serve Chicken Bubble Biscuit Bake Casserole
There are numerous ways to enjoy this Chicken Bubble Biscuit Bake Casserole. For a complete meal, consider pairing it with a fresh green salad drizzled with vinaigrette or some garlicky steamed vegetables on the side. If you want a bit of crunch, a simple coleslaw makes a fantastic accompaniment. This dish can also be served with a warm biscuit on the side for those who enjoy an extra dose of comfort food!
Storage and reheating tips
To keep your leftover Chicken Bubble Biscuit Bake Casserole fresh, store it in an airtight container in the refrigerator. It will stay good for about 3–4 days. For longer storage, you can freeze leftovers in a freezer-safe container for up to 3 months. When ready to enjoy, thaw in the fridge overnight and reheat in the oven at 350°F (175°C) until heated through.
Always remember to practice safe food handling—never leave leftovers out at room temperature for more than 2 hours.
Helpful cooking tips
For the best results, ensure your chicken is cooked and chopped into small, bite-sized pieces before adding it to the casserole. This allows for even cooking and optimal flavor distribution throughout the dish. Don’t hesitate to adjust the seasonings to suit your taste, and consider mixing in different veggies or cheeses to personalize the flavors in this casserole.
Creative twists
The beauty of the Chicken Bubble Biscuit Bake Casserole lies in its versatility. You could easily swap out the cheddar for pepper jack cheese for a spicy kick, or try adding some diced bell peppers for extra color and flavor. If you’re feeling adventurous, toss in some artichoke hearts or spinach for a twist on nutrition. For those who prefer a lighter version, you could use Greek yogurt instead of sour cream!
Common questions
Q: What type of chicken should I use for this casserole?
A: You can use rotisserie chicken for convenience, or cooked chicken breast or thighs that you’ve prepared in advance.
Q: Can I prepare this dish ahead of time?
A: Yes! You can assemble the casserole a day in advance and store it in the refrigerator until you’re ready to bake it.
Q: Is this casserole freezer-friendly?
A: Absolutely! Just make sure it’s covered tightly before freezing. Thaw overnight in the fridge for the best results when reheating.
Q: Can I use alternatives to cream of chicken soup?
A: Yes, you can use homemade cream soups or other cream-based soups for different flavor profiles. Just be aware that it might change the final taste of the casserole.
Enjoy creating this Chicken Bubble Biscuit Bake Casserole and let it become a comforting favorite in your household!






