Step-by-step instructions
Now, let’s get to the cooking part! Follow these simple steps to make your Meat Lovers Pizza Casserole:
- Preheat your oven to 375°F (190°C) and grease a 9×13-inch baking dish.
- In a skillet, brown the ground beef over medium heat until fully cooked. Drain any excess grease.
- Cut the refrigerated biscuits into quarters and spread them evenly across the bottom of your baking dish.
- Layer the cooked ground beef over the biscuits, followed by the pepperoni slices.
- Pour pizza sauce over the layers, ensuring everything is covered.
- Sprinkle the mozzarella and cheddar cheese generously on top.
- Bake in the preheated oven for 25-30 minutes, or until the cheese is melted and the biscuits are golden brown.
- Let the casserole rest for about 5 minutes before diving in. Enjoy!
Best ways to enjoy it
Serving the Meat Lovers Pizza Casserole can be as fun as making it! Consider garnishing with fresh basil or a sprinkle of red pepper flakes for an added kick. Pair it with a simple green salad or some garlic bread to balance out the richness. For a real treat, offer a selection of dipping sauces like ranch or marinara on the side.
Storage and reheating tips
Got leftovers? No problem! Store any remaining casserole in an airtight container in the fridge for up to 3 days. To reheat, simply pop it in the oven at 350°F (175°C) until warmed through, or microwave individual portions if you’re short on time. You can also freeze the casserole before baking for a quick meal later—just be sure to thaw it overnight in the fridge before baking.
Helpful cooking tips
Here are some expert tips to take your casserole to the next level:
- Brown the beef with spices: Add Italian seasoning or garlic powder while browning the meat for extra flavor.
- Cheese layers: Consider mixing different cheese varieties for depth of flavor, like adding pepper jack for some heat.
- Vegetable boost: Sneak in diced bell peppers or mushrooms for added nutrition without sacrificing flavor.
Creative twists
There’s plenty of room for creativity with this casserole! Try using different types of meats, like Italian sausage or ham, or switch up the sauce with pesto or Alfredo for a unique spin. For a healthier option, substitute the biscuits with a cauliflower crust or spiralized zucchini for a low-carb version.
FAQs
Can I prepare this ahead of time?
Absolutely! You can assemble the casserole in advance and store it in the refrigerator. Just pop it in the oven when you’re ready to bake it.
Is it possible to make this dish low-carb?
Yes, you can replace the refrigerated biscuits with a low-carb alternative, such as a cauliflower crust or egg-based crust.
How do I know when the casserole is done?
Check for a bubbly, golden top, and make sure the biscuits are fully cooked through. A toothpick inserted should come out clean without raw dough.
This Meat Lovers Pizza Casserole is not only a delightful meal but also a fantastic way to enjoy the classic flavors of pizza in a more comforting and satisfying form. Enjoy the ease of preparation and the joy it brings to your dining table!






